Going with the Flow: From Circulating Tumor Cells to DNA
Cet article passe en revue les perspectives offertes par l'analyse de l'ADN tumoral circulant pour le développement de biomarqueurs de diagnostic ou de suivi thérapeutique
Molecular analyses of circulating tumor DNA (ctDNA) in plasma from cancer patients have the potential to deliver minimally invasive diagnostic and disease-monitoring biomarkers. Drawing from experience gained through the translation of circulating tumor cell detection to clinical tests, we discuss ctDNA as a source of tumor material for biomarker development.
Science Translational Medicine , résumé, 2013