Use of antineoplastic agents in patients with cancer who have HIV/AIDS
Cet article passe en revue l'usage de chimiothérapies et de thérapies ciblées chez les patients atteints de sida et recevant une tri-thérapie
Highly active antiretroviral therapy (HAART) has substantially reduced morbidity and mortality of AIDS-related complications in patients with HIV; however, the prevalence of AIDS-defining cancers and non-AIDS-defining cancers has increased. In this Review we discuss the management of HAART pharmacotherapy in relation to cytotoxic chemotherapy or targeted antineoplastic agents. We will review potential pharmacological interactions between antiretroviral and antineoplastic therapies and consider how to combine antiretroviral and antineoplastic agents in patients with HIV who are receiving HAART therapy.
The Lancet Oncology , résumé, 2010