Bariatric Surgery Is Preventive Medicine
Menée à partir de données du Danemark, de Finlande et de Suède portant sur 784 105 personnes souffrant d'obésité (âge : 18-59 ans ; 27 % d'hommes), cette étude analyse l’association entre la chirurgie bariatrique et le risque de cancer lié à l’obésité (sein, endomètre, ovaire, oesophage, foie, pancréas, côlon, rectum, rein et myélome multiple) en fonction du sexe et par catégorie d'âge (18-39 ans / 40-59 ans)
Obesity now rivals and is soon expected to overtake smoking as the leading modifiable cause of cancer. Insofar as bariatric surgery is currently the most effective treatment for obesity, it is unsurprising that patients who undergo surgery have a lower risk of developing an obesity-associated cancer. However, it is less clear whether this benefit extends equally across age and sex.The new study by Radkiewicz et al helps answer this question. Using national Nordic registries, the authors followed up roughly 800 000 adults with obesity, about 100 000 of whom underwent bariatric surgery. Compared with patients who did not undergo surgery, those who did had a roughly 20% lower risk of developing an obesity-associated cancer. Just as importantly, the magnitude of this benefit was similar in males and females and in younger and older patients.
JAMA Surgery , éditorial, 2026