Decision and Cost-Effectiveness Analyses Complement Results From Randomized Clinical Trials
Menée à Taïwan à partir d'un modèle de simulation, cette étude estime le rapport coût-efficacité d'un test FIT en combinaison ou non avec un test antigénique fécal recherchant la présence de la bactérie Helicobacter pylori
Decision analysis is a quantitative approach to decision-making under conditions of uncertainty that uses explicit statistically based methods to compare alternative strategies based on their expected outcomes. Cost-effectiveness analysis is a form of decision analysis that compares resource use and health outcomes of competing strategies. The cost-effectiveness analysis by Lee et al in this issue of JAMA estimates that adding 1-time Helicobacter pylori stool antigen testing (HPSA) to fecal immunochemical testing (FIT)–based colorectal cancer screening programs could yield greater life-years and lower costs than FIT alone due to reductions in gastric cancer mortality.
JAMA , éditorial, 2026