Pre-operative Radiotherapy in Locally Advanced Breast Cancer: A Narrative Review
Cette revue narrative fait le point sur le rôle et l'impact de la radiothérapie préopératoire dans la prise en charge d'un cancer du sein localement avancé
Locally-advanced breast cancer (LABC) is a clinically challenging form of BC, requiring a multidisciplinary approach and multimodal therapeutic considerations. The role of radiation therapy (RT) in LABC remains a source of debate, with recent interest in the use of radiation in the pre-operative setting. Outcomes of neoadjuvant RT have been encouraging, with potential benefits in both clinical and cosmetic outcomes. Here we present a narrative review of pre-operative RT in LABC, with an emphasis on clinical considerations, the interplay of chemotherapeutic agents, and the role of neoadjuvant RT in breast reconstruction.
International Journal of Radiation Oncology, Biology, Physics , résumé, 2025