Defining eligibility for lung cancer screening based on individual risk
Menée en Allemagne auprès de 5 191 participants (âge : de 55 à 79 ans ; 57,5 % d'hommes), cette étude compare l'efficacité du modèle PLCOm2012 et des critères de risque NELSON pour identifier les patients nécessitant un dépistage du cancer du poumon par tomographie thoracique à faible dose de rayonnements
Implementation of lung cancer screening is advancing globally, and most countries use categorical eligibility criteria resembling those from randomised low-dose CT screening trials. For example, the US Preventive Services Task Force (USPSTF) requires age 50–80 years, at least 20 pack-years smoked, and 15 years or less of cessation. However, beginning in 2013, studies suggested that defining eligibility using individual lung cancer risk prediction models would yield more lung cancer deaths prevented per population screened
The Lancet Oncology , commentaire, 2025