Thyroid cancer incidence in children and adolescents
Menée à partir de données d'incidence de 49 pays et de mortalité de 27 pays, cette étude analyse les facteurs associés à l'évolution, sur la période 1998-2012, de l'incidence du cancer de la thyroïde chez les enfants et adolescents (âge : inférieur ou égal à 19 ans) ainsi que la mortalité spécifique
Clinically detected thyroid cancer is rare in children, with one to three cases per1 million children per year. The disease—a papillary carcinoma in most cases—is frequentlymore extensive at diagnosis in children than in adults, particularly in children agedyounger than 10 years who often have large thyroid tumours with lymph node and lungmetastases. The overall prognosis is favourable even in cases of metastatic disease, but thetreatment burden can be substantial, and thyroid cancer related deaths that are extremelyrare during childhood and adolescence have been reported several decades after initialdiagnosis, at an adult age. The incidence of clinical thyroid cancer increases with age, and the extent of diseaseis usually less in adolescents and young adults, who have excellent long-term prognoses.
The Lancet Diabetes & Endocrinology , commentaire, 2020