Renal cell carcinoma with isolated lymph node metastases should be reclassified as Stage IV
Menée aux Etats-Unis à partir des données de la base nationale des cancers portant sur 8 988 patients atteints d'un carcinome à cellules rénales de stade III ou IV, cette étude analyse la survie en fonction de la présence d'un envahissement ganglionnaire
On the basis of institutional and population‐based data, it has become clear that the risk of progression is distinctly different for lymph node–positive (LN+)/M0 renal cell carcinoma in comparison with locally advanced, nonmetastatic renal cell carcinoma. It is critical that the American Joint Committee on Cancer staging system recognize the increased risk with LN+/M0 tumors and consider reclassification of LN+/M0 as stage IV.
Cancer , éditorial, 2020