Radio-immunotherapy: the focused beam expands
Mené sur 41 patients atteints d'un cancer métastatique, cet essai évalue l'effet abscopal d'une radiothérapie localisée en combinaison avec l'injection sous-cutanée du facteur de stimulation des colonies de granulocytes et de macrophages
Local treatment of tumour masses by ionising radiation with additional immune stimulation could result in systemic and immune-mediated anti-tumour responses. The abscopal effect of radiotherapy for malignant lymphoma was described by Nobler1 in 1969 and has had a renaissance in the last decade when immunotherapies made their way into the clinics.
The Lancet Oncology , commentaire, 2014