Hormone therapy: short-term relief, long-term consequences
A partir de données de 52 études incluant 12 110 femmes ménopausées, cette méta-analyse évalue l'association entre l'utilisation d'un traitement hormonal substitutif de la ménopause et le risque de cancer de l'ovaire
The decline of a woman's natural hormones during menopause is associated with various symptoms, including hot flashes, night sweats, mood swings, and trouble concentrating. Long-term effects can include bone loss, risk of fractures, and cardiovascular disease. To ameliorate short-term and long-term consequences of menopause, hormone replacement with oestrogen was introduced in the 1940s. The biological mechanisms underlying the associations between hormone use and various conditions are not well understood.
The Lancet , commentaire, 2014