Optimizing Dosing of Oncology Drugs
Cet article passe en revue les défis posés par le choix d'un dosage optimal des médicaments en oncologie
The purpose of this article is to acknowledge the challenges in optimizing the dosing of oncology drugs and to propose potential approaches to address these challenges in order to optimize effectiveness, minimize toxicity, and promote adherence in patients. These approaches could provide better opportunities to understand the sources of variability in drug exposure and clinical outcomes during the development and premarketing evaluation of investigational new drugs.
Clinical Pharmacology & Therapeutics , résumé, 2013