Challenges in circulating tumour cell research
Cet article passe en revue les enjeux actuels de la recherche sur l'intérêt des cellules tumorales circulantes pour le développement clinique de biomarqueurs des cancers
During the past ten years, circulating tumour cells (CTCs) have received enormous attention as new biomarkers and the subject of basic research. Although CTCs are already used in numerous clinical trials, their clinical utility is still under investigation. Many issues regarding the detection and characterization of CTCs remain unknown. In this Opinion article, we propose a conceptual framework of CTC assays and point out current challenges of CTC research, which might structure this dynamic field of translational cancer research.
Nature Reviews Cancer , résumé, 2013