Integration of cancer genomics with treatment selection
Cet article passe en revue les travaux récents sur l'utilisation de données génomiques pour développer de nouveaux biomarqueurs de la réponse thérapeutique chez les patients atteints de cancer
The field of cancer genomics is rapidly advancing as new technology provides detailed genetic and epigenetic profiling of human cancers. The amount of new data available describing the genetic make-up of tumors is paralleled by rapid advances in drug discovery and molecular therapy currently under investigation to treat these diseases. This review summarizes the challenges and approaches associated with the integration of genomic data into the development of new biomarkers in the management of cancer. Cancer 2013. © 2013 American Cancer Society.
Cancer , résumé, 2012