Evolving Panorama of Treatment for Metastatic Pancreas Adenocarcinoma
Mené sur 834 patients atteints d'un cancer du pancréas de stade avancé ou métastatique, cet essai de phase III évalue, du point de vue de la survie globale, l'efficacité d'une fluoropyrimidine orale, S-1, seule ou en combinaison avec la gemcitabine
Pancreas adenocarcinoma in contradistinction to other common solid tumor malignancies such as breast, lung, prostate, and colorectal cancer, has both rising incidence and mortality rates, emphasizing the major public health problem this disease incurs. Nonetheless, the last several years have also seen improved understanding of the molecular pathogenesis and the biology of pancreas adenocarcinoma and tangible progress has been made in the area of therapeutics for advanced disease...
Journal of Clinical Oncology , éditorial en libre accès, 2013