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Targeted Therapeutics

Cet article passe en revue les travaux récents sur l'usage de thérapies géniques et de cellules génétiquement modifiées pour le traitement des cancers

Deciphering the molecular underpinnings of a disease is often only the first step toward developing an effective treatment. The path from target identification to a successful therapeutic can be filled with numerous hurdles that call for creative strategies. This Select highlights recent advances in using gene therapy and engineered cells to treat cancers and chronic heart disease. Their success in preliminary trials suggests that these unconventional strategies are close to becoming mainstream options for refractory diseases.

Cell , résumé, 2010

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