Oral Contraceptives and the Small Increased Risk of Breast Cancer
Menée au Danemark à partir de données portant sur 1,8 million de femmes âgées entre 15 et 49 ans, cette étude de cohorte prospective évalue l'association entre l'utilisation d'une contraception hormonale et le risque de cancer du sein (durée moyenne de suivi : 10,9 ans ; 11 517 cas)
In this issue of the Journal, Mørch et al.1 present the results of a large prospective study of the association between the use of hormonal contraceptives and the risk of breast cancer among women in Denmark who were younger than 50 years of age. They observed a 20% higher risk among women who were currently using or had recently used hormonal contraceptives than among those who had never used them, and the risk increased with a longer duration of use. The association between the current use of oral contraceptives and breast cancer is well established; the relative risk of 1.20 . . .
New England Journal of Medicine , éditorial, 2016