The role of nursing interventions in the management and outcomes of gynecological tumors: a systematic review and meta-analysis
A partir d'une revue systématique de la littérature (10 essais, 1 574 patientes), cette méta-analyse évalue l'intérêt d'interventions menées par des infirmièr(e)s pour prendre en charge les patientes atteintes d'un cancer gynécologique et améliorer leur qualité de vie
Purpose: This meta-analysis evaluates the effectiveness of nurse-led interventions in improving quality of life (QoL), mental health, sexual function, marital satisfaction, postoperative recovery, and symptom distress in gynecological cancer patients.
Methods: A systematic search of PubMed, Embase, Web of Science, Cochrane Library, and PsycINFO identified randomized controlled trials (RCTs) and quasi-experimental studies. A random-effects meta-analysis was conducted, assessing heterogeneity (I2), publication bias, and evidence certainty using the GRADE framework.
Results: Ten RCTs (1,574 participants) showed nurse-led interventions significantly reduced anxiety (d = 0.85–1.29), depression (d = 1.29), and improved QoL (d = 0.42–1.29). Sexual rehabilitation programs enhanced sexual function (d = 0.95) and marital satisfaction (d = 0.65–0.80). Postoperative nursing interventions lowered infection rates (OR = 7.82) and improved recovery. cognitive-behavioral therapy (CBT)-based interventions, when adapted for delivery by trained nurses, had the strongest psychological benefits, while structured postoperative care optimized recovery. Heterogeneity was moderate to high (I2 = 58–72%), and GRADE rated evidence as moderate for anxiety reduction, sexual function, and recovery but low for QoL and patient empowerment.
Conclusion: Nurse-led interventions effectively improve mental health, QoL, sexual function, and recovery in gynecological cancer patients, offering a cost-effective, accessible alternative to physician-led care. Future research should standardize protocols, conduct multicenter trials, and assess long-term impacts.
Supportive Care in Cancer , résumé, 2025