Comparative Effects of Different Types of Exercise Interventions on Depression in Patients With Cancer: A Network Meta-Analysis of Randomized Controlled Studies
A partir d'une revue de la littérature (49 études, 4 738 patients), cette méta-analyse évalue l'efficacité de plusieurs types d'interventions comportant des exercices physiques pour soulager les symptômes de dépression des patients atteints d'un cancer
Background: Depression is a common psychological disorder in patients with cancer. Exercise intervention has been demonstrated as an effective non-pharmacological intervention for improving depression. However, the relative efficacy of different types of exercise interventions remains uncertain.
Objective: To compare the effectiveness of different types of exercise interventions in patients with cancer.
Methods: Seven databases were systematically searched. Two reviewers independently conducted the data extraction and quality assessment. The random effects model was used for the meta-analysis. Traditional pairwise meta-analysis and network meta-analysis were performed via STATA software.
Results: Forty-nine studies with 4738 participants were included. The interventions were categorized as mind-body exercise, aerobic exercise, anaerobic exercise, resistance exercise, combined exercise, and progressive muscle relaxation. Network meta-analysis consistently revealed the greatest therapeutic benefits of aerobic exercise (SUCRA: 68.4%), followed by combined exercise (SUCRA: 66.4%) and resistance exercise (SUCRA: 55.7%).
Conclusions: Exercise has potential benefits for relieving depression in patients with cancer, and it is poised to serve as a valuable complementary or alternative therapy. Large-scale and more rigorous RCTs are needed to evaluate the long-term effects of exercise interventions and examine intervention characteristics related to better intervention outcomes.
Psycho-Oncology , résumé, 2025