Does Air Pollution Reduce Cancer Survival? New Findings from SEER Program Cohorts
A partir des données des registres américains des cancers portant sur 5 591 168 patients atteints d'un cancer et sur 2 318 068 patients ayant survécu 5 ans à un cancer, cette étude analyse l'association entre une exposition à des particules fines et la mortalité, par cancer et par maladie cardiopulmonaire
Air pollution causes cancer[1]; does it also affect outcomes for those developing cancer? Are people with cancer at increased risk for the excess mortality associated with air pollution exposure? Innovatively using cancer patient data from the Surveillance, Epidemiology, and End Results (SEER) Program, Coleman et al. address these questions in this issue of the journal.[2] Their findings come from two separate, but overlapping cohorts constructed within the SEER Program database: one composed of 5.6 million people with incident cancer and the second composed of 2.3 million five-year cancer survivors. Long-term air pollution exposure, indexed by particulate matter less than 2.5 microns in aerodynamic diameter (PM2.5), was estimated for the county of residence using a model that combines regulatory modeling data with other predictors of air pollution levels. Such model estimates have now been widely used in studies of air pollution and health and have well-established accuracy (...)
JNCI Cancer Spectrum , commentaire en libre accès, 2020