Cervical Cancer as a Global Concern: Contributions of the Dual Epidemics of HPV and HIV
Mené au Kenya auprès de 400 patientes atteintes du VIH et présentant des lésions intraépithéliales de haut grade (âge médian : 37,4 ans), cet essai randomisé compare l'efficacité, du point de vue du taux de récidive à 24 mois des lésions précancéreuses, d'un traitement par cryothérapie et d'une résection à l'anse diathermique
Cancer of the uterine cervix is among the most preventable human malignancies, yet it remains a leading cause of death among women worldwide, accounting for more than 300 000 deaths annually. Well on its way to elimination in the global north, cervical cancer mostly affects women living in low- or middle-income countries (LMICs), where limited access to vaccination, screening, and therapy have made it overwhelmingly a disease of women who are poor and lack access to health care. Nowhere is this more evident than in sub-Saharan Africa, where HIV is endemic and where cervical cancer has surpassed breast cancer as the most common and deadly cancer in women.
JAMA , éditorial, 2018