Early-onset colorectal cancer: trends and challenges
Menée dans sept pays à revenus élevés (Australie, Canada, Danemark, Norvège, Nouvelle-Zélande, Irlande, Royaume-Uni), cette étude analyse l'évolution, sur la période 1991-2014, des facteurs associés au risque de cancer colorectal
Since the first report by Bacon and Sealy in 1939, numerous cohort studies have shown a progressive increase in the incidence of early-onset (ie, before age 50 years) colorectal cancer, with incidences of rectal cancer increasing by as much as 75% over the past 45 years in the USA. Data from the Surveillance, Epidemiology, and End Results programme (a US population cancer registry) showed that the incidence of early-onset colorectal cancer doubled between 1991 and 2014 in the USA. Bailey and colleagues subsequently forecasted that the incidence would increase by up to 270% by 2030 in the same population. In 2018, 10% of all colorectal cancers in the USA were diagnosed in people younger than 50 years (generally in people aged 40–49 years).
The Lancet Gastroenterology & Hepatology , commentaire, 2018