Regional variation of computed tomographic imaging in the United States and the risk of nephrectomy
Menée aux Etats-Unis à partir de données portant sur 15 millions de patients bénéficiant de l'assurance maladie Medicare et âgés de 65 à 85 ans, cette étude évalue l'association entre l'utilisation de la tomographie numérique thoracique ou abdominale et le risque de néphrectomie pour une tumeur rénale
Importance : While computed tomography (CT) represents a tremendous advance in diagnostic imaging, it also creates the problem of incidental detection—the identification of tumors unrelated to the clinical symptoms that initiate the test.
Objective : To determine the geographic variation in the United States in CT imaging and the corresponding association with one of the most consequential sequelae of incidental detection: nephrectomy.
Design, Setting, and Participants : This study is a cross-sectional analysis of age-, sex-, and race-adjusted Medicare data (January 2010-December 2014) from 306 hospital referral regions (HRRs) in the United States and includes information from 15 million fee-for-service Medicare beneficiaries age 65 to 85 years.
Exposures : Regional CT risk (ie, the proportion of the population receiving either a chest or abdominal CT over 5 years).
Main Outcomes and Measures : Five-year risk of nephrectomy (partial or total).
Results : Data from 15 million fee-for-service Medicare beneficiaries age 65 to 85 years were gathered and illustrate that 43% of Medicare beneficiaries age 65 to 85 years received either a chest or abdominal CT from January 2010 to December 2014. This risk varied across the HRRs, ranging from 31% in Santa Cruz, California, to 52% in Sun City, Arizona. Increased regional CT risk was associated with a higher nephrectomy risk (r = 0.38; 95% CI, 0.28-0.47), particularly among HRRs with more than 50 000 beneficiaries (r = 0.47; 95% CI, 0.31-0.61). After controlling for HRR adult smoking rates, imaging an additional 1000 beneficiaries was associated with 4 additional nephrectomies (95% CI, 3-5). Case-fatality rates for those who underwent nephrectomy were 2.1% at 30 days and 4.3% at 90 days.
Conclusions and Relevance : Fee-for-service Medicare beneficiaries are commonly exposed to CT imaging. Those residing in high-scanning regions face a higher risk of nephrectomy, presumably reflecting the incidental detection of renal masses. Additional surgery should be considered one of the risks of excessive CT imaging.
JAMA Internal Medicine , résumé, 2016