Vitamin C could target some common cancers
Menée sur des lignées cellulaires à l'aide de modèles murins de cancer colorectal présentant des mutations des gènes KRAS ou BRAF, cette étude met en évidence des mécanismes suggérant l'intérêt thérapeutique de fortes doses de vitamine C
Decades ago, Nobel Prize–winning chemist Linus Pauling was relegated to the fringes of medicine after championing the idea that vitamin C could combat a host of medical conditions, including cancer. Now, a study published online this week by Science reports that vitamin C can kill tumor cells that carry a common cancer-causing mutation and, in mice, can curb the growth of tumors with the mutation. If the findings hold up in people, researchers may have found a way to treat a large swath of tumors that have lacked effective drugs. Because high dose vitamin C is already known to be safe, clinical trials to test this idea could move ahead quickly.
Science , commentaire, 2015