Tonsillectomy and Risk of Oropharyngeal Cancer: Implications for Research and Prevention
Menée à partir des données de registres danois portant sur 3 859 867 résidents nés entre 1920 et 1972 (durée de suivi : 72 701 956 personnes-années ; période de suivi : 1977-2012), cette étude évalue l'effet d'une amygdalectomie sur le risque de carcinome de l'oropharynx ainsi que son intérêt pour améliorer la survie globale des patients atteints d'un carcinome de l'amygdale
The association of tonsillectomy, a common surgical procedure involving the removal of a majority of the palatine tonsillar tissue, with risk of tonsil cancer specifically or oropharyngeal cancers overall is not known. In this issue of Cancer Prevention Research, Fakhry and colleagues conduct an analysis within the Danish Cancer Registry and show that tonsillectomies were associated with significantly reduced risk of tonsil cancer, but were unrelated to risk of base of tongue cancers. This editorial discusses the implications of the results by Fakhry and colleagues for key prevailing questions in the field related to risk, rising incidence, secondary prevention, and treatment of oropharyngeal cancers.
Cancer Prevention Research , éditorial, 2015