Radiation induced bowel injury: a neglected problem
Mené sur 218 patients présentant des symptômes gastro-intestinaux après une radiothérapie pelvienne (âge : ≥18 ans), cet essai randomisé contrôlé évalue, du point de vue de l'évolution du degré de sévérité des symptômes et du niveau de dysfonctionnement de l'intestin, la performance d'un algorithme clinique destiné à réduire les effets indésirables liés au traitement
Stigma associated with radiation induced bowel injury (RBI) has restricted interest in its pathogenesis and the pathophysiological processes that occur as a consequence. This neglect has in turn hampered clinical management and led to the widely held belief that RBIs are not amenable to treatment. RBI is more common than Crohn's disease, yet attracts a fraction of the research funding. Furthermore, only a fifth of patients with RBI in the UK see a gastroenterologist, and most who do so are manag ...
The Lancet , commentaire, 2012