Informing Patient Decisions Regarding Management of Ductal Carcinoma In Situ
Menée à partir d'un modèle de simulation pour que les patientes atteintes d'un carcinome canalaire in situ puissent estimer les diverses conséquences de leur choix thérapeutique, cette étude analyse, du point de vue de la survie globale, l'efficacité de six stratégies
The Institute of Medicine has identified the management of ductal carcinoma in situ (DCIS) as one of the highest priority topics for comparative effectiveness research. With the rise of mammographic screening, the incidence of DCIS has increased dramatically, and currently about a quarter of all newly diagnosed breast cancers are DCIS. Although DCIS is by definition noninvasive, treatment is necessary because of the risk of development into invasive cancer. Therefore, most patients with DCIS face complex management decisions, including whether to undergo breast-conserving surgery or mastectomy, as well as whether to receive adjuvant radiotherapy and/or tamoxifen...
Journal of the National Cancer Institute , éditorial en libre accès, 2013