The Cardiovascular Perils of Cancer Survivorship
Menée en Suède et au Danemark sur 2 168 patientes atteintes d'un cancer du sein traité par radiothérapie entre 1958 et 2001, cette étude cas-témoins évalue, en fonction de la dose de rayonnements reçus, le taux de cardiopathie ischémique après traitement et identifie les facteurs de risque associés (963 cas et 1 205 témoins)
Since 1990, breast cancer mortality has decreased yearly in developed nations. In 2012, there were an estimated 3 million survivors of breast cancer in the United States alone.1 This decrease in mortality can be partly attributed to effective treatment strategies developed through collaborations among breast surgeons and medical and radiation oncologists. Radiation therapy has evolved as a critical component of treatment for women who have undergone breast-conservation surgery and for those with a high risk of recurrence who have undergone mastectomy.2 Older radiation techniques for breast cancer are associated with subsequent cardiac disease. Less clear is the cardiac risk associated . . .
New England Journal of Medicine , éditorial, 2012